The Effectiveness of Dextrose Prolotherapy in Patients With Coccydynia
Istanbul University
40 participants
Jun 15, 2025
INTERVENTIONAL
Conditions
Summary
In this prospective, randomized, controlled, double-blinded study, we aimed to evaluate the effects of Dextrose Prolotherapy injections in patients with coccydynia.
Eligibility
Inclusion Criteria4
- Patients with coccydynia lasting longer than 6 months,
- Those unresponsive to at least 6 months of conventional conservative treatment methods,
- Those with coccygeal tenderness on palpation,
- Patients aged between 18 and 65 years.
Exclusion Criteria12
- Patients with a history of trauma within the last 3 months or postpartum coccydynia,
- Those with lesions or infections at the injection site,
- Those with dislocation or organic bone pathology of the coccyx observed on X-ray imaging,
- Those with fecal or urinary incontinence,
- Patients with poorly controlled diabetes mellitus,
- Those with a history of malignancy,
- Patients with a bleeding tendency (acquired or hereditary) \[INR > 2 in patients using warfarin\],
- Those with a history of myelomeningocele,
- Those diagnosed with spina bifida,
- Patients with rheumatologic disease,
- Those who have undergone coccyx injection or ganglion block within the last 3 months,
- Patients with severe comorbidities.
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Interventions
Coccyx injection: Using a sterile 27-gauge syringe (dental needle), a total of 10 cc of solution (5 cc of 30% dextrose + 4 cc of physiological saline + 1 cc of 1% lidocaine solution) will be injected perpendicularly to the surface at the previously marked attachment points of the sacrococcygeal-sacro-tuberous ligaments to the sacrum and along the entire coccyx.
Saline + lidocaine group injection protocol: Using a sterile 30-gauge syringe (insulin needle), a total of 10 cc of solution (5 cc of physiological saline + 5 cc of 1% lidocaine solution) will be injected into the previously marked tendon attachment points on the bone.
Locations(1)
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NCT07552298