ClinicalTrialsFinder
RecruitingNot ApplicableNCT07552948

Radial vs Vena No-Touch Assessment

A Comparative Study of the Effectiveness of Radial Artery and No-touch Vein in Coronary Artery Bypass Grafting in Women

Sponsor

Tomsk Cardiology Research Institute

Enrollment

110 participants

Start Date

Apr 6, 2026

Study Type

INTERVENTIONAL

Conditions

Coronary Artery Atherosclerosis

Summary

This study examines the outcomes of coronary artery bypass grafting (CABG) in women at 1 year after surgery. A randomized controlled trial is planned, including a comparative analysis of two observed groups depending on the chosen conduit for revascularization of the circumflex artery. The main group is supposed to include 55 patients undergoing CABG with the use of the radial artery, while the control group will include 55 patients undergoing CABG with the use of the great saphenous vein prepared using the no-touch technique.

Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria4

  • Three-vessel disease involving the target circumflex artery with stenosis ≥70% and a diameter ≥1.5 mm
  • Females aged 18 years and older
  • Signed informed consent
  • Clinical indications for coronary revascularization (refractory angina/transient myocardial ischemia according to noninvasive tests)

Exclusion Criteria8

  • Previous cardiac surgery of any type, including CABG
  • Combined procedures
  • Ineligibility for venous or radial artery harvesting as determined by preoperative Doppler flowmetry or clinical examination that would compromise graft patency.
  • Acute myocardial ischemia
  • EF less than 35%
  • CKD 4.5
  • Inability to understand the nature, scope, and consequences of the clinical trial, or to provide written informed consent due to cognitive impairment or mental illness.
  • Life expectancy less than 1 year due to non-cardiac diseases.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREradial artery graft

Circumflex artery territory revascularization using the radial artery graft

PROCEDUREno-touch vein graft

Circumflex artery territory revascularization using a no-touch vein graft

Locations(1)

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia

Tomsk, Russia

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07552948