Post-Extraction Healing: microRepair vs Chlorhexidine
Evaluation of Healing in Post-Extraction Sockets Using microRepair Abx Mousse Mouthwash Versus 0.20% Chlorhexidine
University of Roma La Sapienza
30 participants
Sep 1, 2024
INTERVENTIONAL
Conditions
Summary
This randomized clinical trial evaluates the efficacy of a microRepair ABX mouthwash mousse compared to 0.20% chlorhexidine in promoting wound healing following tooth extraction. The study monitors clinical parameters such as pain, swelling, and healing indices at 1, 7, and 15 days post-surgery. The primary objective is to determine if the microRepair ABX technology enhances tissue regeneration and reduces post-operative complications.
Eligibility
Inclusion Criteria8
- Age range: Patients between 18 and 75 years of age.
- Indication for tooth extraction: Specifically for cases involving:
- Destructive caries that do not allow for conservative or prosthetic recovery.
- Untreatable endodontic and/or periapical lesions.
- Advanced periodontal lesions with significant loss of supporting tissue.
- Traumatic lesions involving root fractures (vertical or at the middle third).
- Malpositioned teeth causing functional alterations.
- Roots that cannot be prosthetically recovered or residual roots.
Exclusion Criteria3
- Age: Patients under 18 or over 75 years of age. Systemic Conditions: Presence of immunodepression or immunocompromisation (e.g., HIV infection).
- Pregnancy and Lactation: Women who are currently pregnant or breastfeeding. Mental Health: Presence of psychiatric disorders. Tobacco Use: Severe smokers, defined as consuming more than 10 cigarettes per day.
- Substance Abuse: History of alcohol or drug abuse.
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Interventions
Topical application of the mousse on the surgical wound starting from the day after the extraction. The mousse is specifically formulated to promote healing through microparticles that accelerate tissue repair and an antibacterial complex to prevent localized infections.
Application of 0.20% Chlorhexidine liquid mouthwash. Used as a control treatment to evaluate the comparative effectiveness of the test product in reducing plaque, pain, and inflammation while promoting socket healing.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07555366