RecruitingPhase 2NCT07557446

A Dose REgimen-Finding Study of AGA2115 in Chinese Patients With Osteogenesis ImpeRfecta (EIR)

A Phase 2 Multi-center, Randomized, Open-Label, Dose Regimen-Finding Study of AGA2115 in Chinese Adults and Adolescents With Type I, III, or IV Osteogenesis Imperfecta

Sponsor

Angitia Biopharmaceuticals Guangzhou Limited

Enrollment

48 participants

Start Date

Jun 1, 2026

Study Type

INTERVENTIONAL

Conditions

Osteogenesis Imperfecta (OI)

Summary

This study is to evaluate the safety and efficacy of AGA2115 at three different dose regimens in Chinese adults and adolescents with Type I, III, or IV Osteogenesis imperfecta (OI).

Eligibility

Min Age: 12 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called AGA2115 for people with osteogenesis imperfecta (oi). The study is currently recruiting participants at 4 locations. People eligible for this study include aged 12 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGAGA2115

Participants will receive AGA2115 administered by subcutaneous injection

Locations(4)

Chinese Academy of Medical Sciences, Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

The University of Hong Kong-Shenzhen Hospital

Shenzhen, Guangdong, China

Children's Hospital of Soochow University

Suzhou, Jiangsu, China

Shanghai Sixth People's Hospital

Shanghai, Shanghai Municipality, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07557446

Related Trials

Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)

NCT0706258826 locations

Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta

NCT072872411 location