RecruitingNCT07557498

Mavacamten Outcomes in Hypertrophic Cardiomyopathy (HCM) and the Associated Patient and Physician Experiences in the US

Mavacamten Real-World OutcomeS and the Associated PAtient and Physician ExpeRienCe With Hypertrophic CardioMyopathy in the United States (US) Community


Sponsor

Bristol-Myers Squibb

Enrollment

362 participants

Start Date

Jan 15, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to understand the real-world clinical outcomes and treatment patterns of adults with obstructive hypertrophic cardiomyopathy (HCM) treated with mavacamten, and to understand patient and physician experiences with mavacamten treatment, in the US community-based practice


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • Phase I: retrospective chart review
  • For inclusion in the study, participants must meet ALL of the following criteria:
  • Are an adult aged 18 or over at baseline
  • Have a confirmed diagnosis of obstructive hypertrophic cardiomyopathy (HCM)
  • Have been prescribed mavacamten for obstructive HCM at one of the study sites between 28th April 2022 and 31st December 2024
  • Have not ever been enrolled in any interventional clinical trial involving any cardiac myosin inhibitor (enrollment in observational studies is permitted)
  • Are not enrolled in any interventional clinical trial at study baseline

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Interventions

DRUGMavacamten

According to the product label


Locations(1)

Adelphi Real World

Bollington, Macclesfield, United Kingdom

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NCT07557498


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