Reframing Endometrial Physiology by Advanced Integrated Research
University Hospital Southampton NHS Foundation Trust
100 participants
Feb 6, 2026
OBSERVATIONAL
Conditions
Summary
Heavy menstrual bleeding (HMB) affects 1 in 3 women and can significantly impact quality of life. Despite its prevalence, there is no accessible and accurate diagnostic test. This research will use wearable sensors, magnetic resonance imaging (MRI) scans, and biological sample collection to identify changes in the uterus linked with HMB. The investigators aim to recruit approximately 130 participants across two study sites over three years, including people with and without HMB.
Eligibility
Inclusion Criteria2
- -45
- Having Periods
Exclusion Criteria5
- Currently pregnant or breastfeeding.
- Known uterine malignancy, severe anaemia requiring urgent treatment, or other acute gynaecological emergencies.
- Inability to undergo MRI (e.g., pacemaker, severe claustrophobia).
- Inability to provide informed consent.
- Current use of hormonal treatment, or use in the last 2 months
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07557992