RecruitingPhase 2NCT07561294

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to Prevent Lyme Disease in Healthy Participants (18 to 70 Years of Age)

A Phase 2, Randomized, Observer-blind, Dose-finding, Placebo-controlled Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982, an mRNA Vaccine to Prevent Lyme Disease in Healthy Adult Participants (18 to 70 Years of Age)

Sponsor

ModernaTX, Inc.

Enrollment

350 participants

Start Date

Apr 29, 2026

Study Type

INTERVENTIONAL

Conditions

Lyme Disease

Summary

This clinical study will evaluate the safety, reactogenicity, and immunogenicity of monovalent mRNA-1982, a messenger ribonucleic acid (mRNA) vaccine to prevent Lyme disease in healthy adults aged 18 to 70 years old.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Placebo and a biological treatment called mRNA-1982 for people with lyme disease. The study is currently recruiting participants at 8 locations. People eligible for this study include aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALmRNA-1982

Suspension for injection

BIOLOGICALPlacebo

Suspension for injection

Locations(8)

Colchester Research Group

Truro, Nova Scotia, Canada

Bluewater Clinical Research Group Inc.

Sarnia, Ontario, Canada

Stouffville Medical Research Institute Inc.

Stouffville, Ontario, Canada

Dr. Anil K. Gupta Medicine Professional Corporation Inc.

Toronto, Ontario, Canada

Diex Recherche Inc. - Division Joliette

Joliette, Quebec, Canada

Diex Recherche Inc. - Division Sherbrooke

Sherbrooke, Quebec, Canada

Diex Recherche Inc. - Division Victoriaville

Victoriaville, Quebec, Canada

Diex Recherche Inc. - Division Quebec

Québec, Canada

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07561294

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