ClinicalTrialsFinder
RecruitingNot ApplicableNCT07562334

Assessment of Soft Tissue Thickness Following Utilization of Buccal Pad of Fat Versus Platelet-rich Fibrin for Covering Zygomatic Implants: A Randomized Clinical Trial

Sponsor

Cairo University

Enrollment

24 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Soft Tissue Augmentation at Dental Implants

Summary

Would buccal pad of fat be comparable to platelet rich fibrin for Zygomatic implant coverage as a step for reconstruction of atrophic posterior maxilla, in terms of peri-implant soft tissue thickness and avoiding complicated postoperative sequalae?

Eligibility

Inclusion Criteria5

  • Patients with severely atrophic edentulous upper arch (Cawood class IV, V, VI) that could not be restored by other type of treatment
  • Patients who had at least 8-12 mm vertical bone height in anterior maxilla to allow installation of 2 conventional implants.
  • Lacking posterior maxillary bone support due to significant sinus pneumatization
  • Good systemic health (ASA score I-II)
  • Highly motivated patients

Exclusion Criteria7

  • Patient not willing to give his/her informed consent.
  • Patients with systemic disease that did not permit the surgical procedure (including general anesthesia).
  • Patients with uncontrolled diabetes or under bisphosphonate therapy.
  • Heavy smoker. (> 20 cigarettes daily)
  • Patient with psychiatric problems, severe bruxism or other parafunctional habits.
  • Acute sinusitis.
  • Malignancy or pathology in Maxilla or Zygoma.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BIOLOGICALCoverage with PRF for Zygomatic implant placed

PRF preparation and placement: Shortly before being positioned at the surgical site, the PRF was freshly prepared. Ten milliliters of blood were extracted from the antecubital vein and put into a test tube devoid of anticoagulant for the PRF preparation. The blood sample was centrifuged right away for 10-12 minutes at 3000 rpm. The PRF membrane was obtained by squeezing the fibrin clot between pieces of gauze after centrifugation

Locations(1)

Cairo university, Faculty of dentistry

Cairo, Cairo Governorate, Egypt

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07562334

Related Trials

Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis

NCT074713861 location