RecruitingEarly Phase 1NCT07565753

TEAPOT Study Multisite

TranExamic Atomized for Pediatric Post-Operative Tonsillectomy Hemorrhage (TEAPOT): A Multi-center Feasibility Study


Sponsor

The University of Texas Health Science Center at San Antonio

Enrollment

30 participants

Start Date

Jul 14, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

After a child has their tonsils removed, sometimes they might bleed which can be a problem. There is a special mist medicine called nebulized tranexamic acid (TXA) that might help stop the bleeding without having to touch the sore spot. If this mist works well, it could help kids get better by making sure they don't have to go back for more surgery or need blood from someone else. Not having another surgery is good because it means kids won't have to sleep under medicine again, which can sometimes be risky for their brains and breathing, and they won't feel as scared or hurt.


Eligibility

Min Age: 2 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Normal Saline and a drug called Tranexamic Acid Injectable Product for people with hemorrhage, surgical and tonsillar bleeding. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 2 Years to 17 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTranexamic Acid Injectable Product

Participants will receive three doses of TXA 500 mg (5 mL of TXA 100mg/ml) nebulized using a PARI LC D Disposable Nebulizer or equivalent over 10-15 minutes using 8 or greater liter/minute of gas flow.

OTHERNormal Saline

Participants will receive three 5 ml doses of placebo (normal saline) nebulized using a PARI LC D Disposable Nebulizer or equivalent over 10-15 minutes using 8 or greater liter/minute of gas flow.


Locations(3)

University of California at Davis Medical Center

Davis, California, United States

Hasbro Childrens' Hospital

Providence, Rhode Island, United States

University Hospital

San Antonio, Texas, United States

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NCT07565753


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