RecruitingPhase 3NCT07575399

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

A Phase 3, Open-label Trial to Evaluate the Efficacy, Safety and Tolerability of Switching From the Glucagon-like Peptide-1 Receptor Agonists to Maridebart Cafraglutide in Adult Participants With Obesity or Overweight

Sponsor

Amgen

Enrollment

300 participants

Start Date

May 11, 2026

Study Type

INTERVENTIONAL

Conditions

Obesity or Overweight

Summary

Efficacy, safety and tolerability of switching from GLP-1RA to maridebart cafraglutide in adults with obesity or overweight.

Eligibility

Min Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Maridebart Cafraglutide for people with obesity or overweight. The study is currently recruiting participants at 40 locations. People eligible for this study include aged 18 Years to 99 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMaridebart Cafraglutide

Maridebart cafraglutide will be administered via subcutaneous (SC) injection.

Locations(40)

Cahaba Research, Inc.

Pelham, Alabama, United States

Arizona Clinical Trials

Chandler, Arizona, United States

Epic Medical Research - Sun City

Sun City, Arizona, United States

Desert Oasis Healthcare Medical Group

Palm Springs, California, United States

Inland Empire Liver Foundation

Rialto, California, United States

Peninsula Research Associates

Rolling Hills Estates, California, United States

Apex Clinical Research

San Diego, California, United States

Southern California Clinical Research

Santa Ana, California, United States

Aga Clinical Trials

Hialeah, Florida, United States

South Florida Clinical Research

Margate, Florida, United States

New Horizon Research Center

Miami, Florida, United States

Research Institute of South Florida

Miami, Florida, United States

Clinical Neuroscience Solutions

Orlando, Florida, United States

Florida Institute for Clinical Research

Orlando, Florida, United States

Progressive Medical Research

Port Orange, Florida, United States

Charter Research - The Villages

The Villages, Florida, United States

Nsc Research

Johns Creek, Georgia, United States

Rophe Adult and Pediatric Medicine/Sky Clinical Research Network Group

Union City, Georgia, United States

North Georgia Clinical Research

Woodstock, Georgia, United States

Solaris Clinical Research

Meridian, Idaho, United States

Endeavor Health

Skokie, Illinois, United States

Arcturus Healthcare, Public Limited Company, Troy Internal Medicine Research Division

Troy, Michigan, United States

Sky Integrative Medical Center

Ridgeland, Mississippi, United States

Excel Clinical Research

Las Vegas, Nevada, United States

Rochester Clinical Research

Rochester, New York, United States

Centricity Research Morehead City Specialty

Morehead City, North Carolina, United States

Accellacare of Raleigh

Raleigh, North Carolina, United States

Accellacare Research of Wilmington

Wilmington, North Carolina, United States

Lynn Health Science Institute

Oklahoma City, Oklahoma, United States

Altoona Center for Clinical Research

Duncansville, Pennsylvania, United States

Epic Medical Research - DeSoto

DeSoto, Texas, United States

South Texas Research Institute

Edinburg, Texas, United States

Biopharma Informatic, LLC

Houston, Texas, United States

Research Physicians Network, LLC

Houston, Texas, United States

Texas Institute of Cardiology

McKinney, Texas, United States

North Hills Medical Research

North Richland Hills, Texas, United States

VIP Trials

San Antonio, Texas, United States

Northwest Houston Heart Center

Tomball, Texas, United States

Eastside Research Associates Health Research

Redmond, Washington, United States

Puerto Rico Medical Research Inc.

Ponce, Puerto Rico

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07575399

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