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Quantifying Blood Flow in the Aorta

Quantifying Blood Flow in the Aorta Using Phase-Contrast 4D Flow MRI - Phase 2

Sponsor

University of Twente

Enrollment

70 participants

Start Date

Jun 1, 2026

Study Type

OBSERVATIONAL

Conditions

Healthy Aortic Blood Flow

Summary

This study aims to gain insights into aortic blood flow in healthy volunteers using PC 4D-flow MRI

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria5

  • Healthy (in particular without any cardiovascular disease or history thereof) men or women
  • years of age or above;
  • BMI ≤ 30;
  • Willingness to undergo MRI scans;
  • Able to provide signed informed consent (IC)

Exclusion Criteria2

  • Irregular heartbeat.;
  • Any history of cardiovascular disease or current cardiovascular disease;

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Interventions

OTHER4D-flow Magnetic Resonance Imaging

Subjects will undergo MRI scans of the thorax and abdomen from which we will derive aortic blood flow velocity fields. This intervention will be performed in the same manner on all groups.

OTHERQuestionnaires

Subjects fill in a questionnaire regarding their weight, height, age and gender. They also fill in a safety check form to test if MRI can be applied safely.

Locations(1)

TechMed centre, University of Twente

Enschede, Overijssel, Netherlands

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NCT07577752