RecruitingNot ApplicableNCT07580989

Network Effects of Left M1 rTMS: A TMS-EEG Study

Effects of Left Primary Motor Cortex rTMS on Cortical Connectivity Assessed With TMS-EEG Across Left M1, Right M1, Premotor, and Occipital Cortices

Sponsor

Aalborg University

Enrollment

20 participants

Start Date

May 1, 2026

Study Type

INTERVENTIONAL

Conditions

Cortical Plasticity

Summary

This study investigates the modification of connectivity patterns in response to one session of active repetitive transcranial magnetic stimulation (rTMS) applied to the primary motor cortex. Transcranial magnetic stimulation (TMS) will be applied to elicit electroencephalography (EEG) responses in healthy volunteers. TMS-evoked potentials (TEPs) will be recorded before and after the rTMS session and will serve as a reflection of cortical connectivity to TMS. Four cortical targets will be stimulated for TMS-EEG assessment: left primary motor cortex, right primary motor cortex, left premotor cortex, and right occipital cortex.

Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying rTMS for people with cortical plasticity. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERrTMS

Repetitive transcranial magnetic stimulation (rTMS) is applied to the primary motor cortex. The protocol consists of 15 minutes of 10Hz stimulation, 10 seconds on, 20 seconds off, at 90% RMT, for a total of 3000 pulses.

Locations(1)

Aalborg University

Gistrup, Denmark

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NCT07580989