RecruitingNot ApplicableNCT07582731

A Multi-Center Randomized Controlled Trial on the Impact of Disease Subtype-Based Active Video Education on Bowel Preparation Quality in Patients With Inflammatory Bowel Disease


Sponsor

Jie Liang

Enrollment

600 participants

Start Date

Jun 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This multi-center, prospective, randomized controlled trial evaluates whether disease subtype-based active video education improves bowel preparation quality in patients with inflammatory bowel disease (IBD) undergoing colonoscopy. A total of 600 IBD patients from 13 centers will be randomized 1:1 to standard education plus subtype-specific video education (intervention group) or standard education alone (control group). The primary outcome is the Boston Bowel Preparation Scale (BBPS) score.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria5

  • Age between 18 and 75 years, inclusive.
  • Confirmed diagnosis of Ulcerative Colitis (UC) or Crohn's disease (CD) according to standard clinical guidelines.
  • Scheduled for elective colonoscopy for IBD monitoring or disease activity assessment.
  • Able to understand written and verbal instructions and to use a smartphone to view video education materials.
  • Voluntary participation with written informed consent.

Exclusion Criteria7

  • Absolute contraindications to colonoscopy, including acute gastrointestinal perforation, fulminant colitis, toxic megacolon, or hemodynamic instability.
  • History of total or subtotal colectomy.
  • Acute or chronic intestinal obstruction.
  • Severe cardiac, pulmonary, hepatic, or renal insufficiency (eGFR <30 mL/min/1.73m², NYHA class III/IV).
  • Severe psychiatric or cognitive impairment that prevents understanding of the study requirements.
  • Inability or unwillingness to provide written informed consent.
  • Pregnant or breastfeeding women.

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Interventions

BEHAVIORALDisease Subtype-Based Active Video Education

A structured, subtype-specific educational video program tailored for patients with inflammatory bowel disease (IBD). The videos are customized based on IBD subtype (ulcerative colitis/Crohn's disease), disease activity (active/remission), and Crohn's disease behavior (stricturing/fistulizing). It covers key topics including dietary restrictions, laxative intake instructions, symptom management, and practical problem-solving strategies to improve understanding and adherence to bowel preparation protocols. The video is delivered via WeChat link.

BEHAVIORALstandard bowel preparation education

standard bowel preparation education


Locations(12)

Peking Union Medical College Hospital

Beijing, BeijingBeijing, China

Shengjing Hospital of China Medical University

Shenyang, Liaoning, China

Affiliated Hospital of Qinghai University

Xining, Qinghai, China

The Second Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, China

Air Force 986 Hospital

Xi'an, Shaanxi, China

Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

Renji Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

Changhai Hospital, Naval Medical University

Shanghai, Shanghai Municipality, China

Heping Hospital affiliated to Changzhi Medical College

Changzhi, Shanxi, China

Linfen Central Hospital

Linfen, Shanxi, China

Yuncheng Central Hospital

Yuncheng, Shanxi, China

The First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, China

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NCT07582731


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