DELAYED VERSUS EARLY SURGICAL DECOMPRESSION FOR TRAUMATIC SPINAL CORD INJURY
COMPARISON OF DELAYED VERSUS EARLY SURGICAL DECOMPRESSION FOR TRAUMATIC SPINAL CORD INJURY
Fauji Foundation Hospital
100 participants
Aug 30, 2025
OBSERVATIONAL
Conditions
Summary
To compare the outcome of early versus delayed surgical decompression among patients presenting with traumatic spinal cord injury in a tertiary care hospital.
Eligibility
Inclusion Criteria3
- Patients presenting with spinal cord injury (both cervical and thoracic) as per described in the operational definition
- Age from 18-60 years
- Both male and female patients
Exclusion Criteria9
- Patients with penetrating spinal injuries such as gunshot/stab wounds
- Patients with pre-existing neurological conditions like myelopathy etc.
- Patients with any kind of malignancy
- Patients having CSF infection etc.
- Patients who are not fit for general anesthesia (i.e. ASA Grade >2 Annexure-B)
- Diagnosis of subclinical or clinical polyneuropathy
- Non-traumatic or pathological fractures or cord compression
- Inability to cooperate with preoperative physical examination because of cognitive impairment
- Patients with previous spinal column or SCI.
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Interventions
it will be defined as the surgical decompression performed within 24 hours of injury. It will be performed among all the patients who presented within 24 hours of injury.
It will be defined as the surgical decompression performed after 24 hours of spinal cord injury. It will be performed among all the patients who needed it due to medical optimization (such as hemodynamically unstable, shock, pulmonary contusions, cerebrovascular destabilization etc.) or those who will present after 24 hours of injury due to logistical delay.
Locations(1)
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NCT07583836