RecruitingPhase 1Phase 2NCT07587515

Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration

Open-Label, Multiple Ascending Dose Phase 1b/2a Study of the Safety and Tolerability of Intravitreal (IVT) EYC-0305 in Patients With Neovascular Age-Related Macular Degeneration


Sponsor

Eyconis INC.

Enrollment

30 participants

Start Date

May 19, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This Phase 1b/2a study will primarily investigate the safety and tolerability of EYC-0305 delivered by intravitreal (IVT) injection every 24 weeks in patients with neovascular (wet) age-related macular degeneration (AMD). The pharmacokinetics (PK) and immunogenicity of EYC-0305, and the effect on disease activity and vision will also be evaluated.


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called EYC-0305 for people with neovascular (wet) age-related macular degeneration. The study is currently recruiting participants at 6 locations. People eligible for this study include aged 50 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALEYC-0305

Extended-delivery anti-VEGF


Locations(6)

Beverly Hills, CA

Beverly Hills, California, United States

Wake Forest, NC

Wake Forest, North Carolina, United States

Erie, PA

Erie, Pennsylvania, United States

Bellaire, TX

Bellaire, Texas, United States

McAllen, TX

McAllen, Texas, United States

The Woodlands, TX

The Woodlands, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07587515


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