RecruitingNCT07595653

A Study to Evaluate the Impact of Efgartigimod on Overall Disease Experience of People Suffering From Generalized Myasthenia Gravis (gMG) in Italy

Non-interventional, Longitudinal Hybrid Data Sources Study to Evaluate the Impact of Efgartigimod on Overall Disease Experience of People Suffering From Generalized Myasthenia Gravis (gMG) in Italy


Sponsor

argenx

Enrollment

100 participants

Start Date

Feb 25, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to generate real world evidence (RWE) from Italian clinical practice on the impact of efgartigimod alfa in gMG patients encompassing clinical outcomes and patient reported experiences. The study population will consist in adult patients with a documented diagnosis of gMG who are AChR-antibody positive and for whom the decision of treatment with efgartigimod alfa for gMG has been made independently of study participation as part of routine clinical care. The total study duration will be up to 23 months


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • At least 18 years old at signing of informed Consent Form (ICF) and privacy form (PF)
  • Documented diagnosis of gMG
  • AChR-antibody positive
  • The treating physician has decided to initiate efgartigimod alfa as part of routine clinical care and in accordance with product labelling, independently from the study

Exclusion Criteria2

  • Hypersensitivity to the active substance or to any of the excipients listed: sodium dihydrogen phosphate, monohydrate; disodium hydrogen phosphate, anhydrous; arginine hydrochloride; polysorbate 80, hyaluronidase, histidine, histidine hydrochloride monohydrate, methionine, polysorbate 20, sucrose.
  • Current or planned participation in an interventional clinical trial.

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Locations(30)

Ospedale Generale Regionale F. Miulli

Acquaviva delle Fonti, Italy

Azienda Ospedaliero Universitaria delle Marche

Ancona, Italy

A.O.U. Consorziale Policlinico

Bari, Italy

ASST Papa Giovanni XXIII

Bergamo, Italy

Ospedale Bellaria

Bologna, Italy

A.O.U. Renato Dulbecco

Catanzaro, Italy

A.O.U. Careggi

Florence, Italy

IRCCS Ospedale Policlinico San Martino

Genova, Italy

A.O.U. Policlinico G. Martino

Messina, Italy

IRCCS Cà Granda Ospedale Maggiore Policlinico

Milan, Italy

Ospedale San Raffaele

Milan, Italy

IRCCS Istituto Neurologico Carlo Besta

Milan, Italy

ASST GOM Niguarda

Milan, Italy

A.O.U. Policlinico Universitario

Monserrato, Italy

AORN A. Cardarelli

Naples, Italy

A.O.U. Università della Campania L. Vanvitelli

Naples, Italy

A.O.U. San Luigi Gonzaga

Orbassano, Italy

Azienda Ospedale Università Padova

Padova, Italy

IRCCS Fondazione Mondino

Pavia, Italy

Azienda Ospedaliera Perugia

Perugia, Italy

A.O.U. Pisana

Pisa, Italy

Ospedale degli Infermi

Rimini, Italy

Fondazione PTV Policlinico Tor Vergata

Roma, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Roma, Italy

Ospedale Sant'Andrea

Roma, Italy

A.O.U. San Giovanni di Dio e Ruggi D'Aragona

Salerno, Italy

IRCCS Fondazione Casa Sollievo della Sofferenza

San Giovanni Rotondo, Italy

A.O.U. Sassari

Sassari, Italy

Ospedale Ca' Foncello

Treviso, Italy

AOUI Verona - Policlinico G.B. Rossi

Verona, Italy

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NCT07595653


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