RecruitingPhase 1NCT07597200

A Clinical Study of Cizutamig in Thyroid Eye Disease

A Phase 1b, Open-Label, Multicenter Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Preliminary Clinical Activity of Cizutamig in Patients With Thyroid Eye Disease

Sponsor

Candid Therapeutics

Enrollment

38 participants

Start Date

May 8, 2026

Study Type

INTERVENTIONAL

Conditions

Thyroid Eye Disease (TED)

Summary

The purpose of this study is to evaluate the safety, tolerability, PK, PD, immunogenicity, and preliminary clinical activity of cizutamig in patients with thyroid eye disease (TED).

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Cizutamig will be dosed according to the protocol. for people with thyroid eye disease (ted). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCizutamig will be dosed according to the protocol.

CND106

Locations(14)

The Second Hospital of Anhui Medical University

Hefei, Anhui, China

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

Fujian Medical University Union Hospital

Fuzhou, Fujian, China

The Eighth Affiliated Hospital of Southern Medical University (Shunde District People's Hospital of Foshan City)

Foshan, Guangdong, China

Guangdong Provincial People's hospital

Guangzhou, Guangdong, China

Xiangya Hospital of Central South University

Changsha, Hubei, China

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

The Third Xiangya Hospital of Central South University

Changsha, Hunan, China

The First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China

The Second Hospital of Dalian Medical University

Dalian, Liaoning, China

The First Affiliated Hospital of China Medical University

Shenyang, Liaoning, China

Qilu Hospital of Shandong University

Jinan, Shandong, China

Shanghai Ninth People's hospital Shanghai Jiaotong University school of medicines

Shanghai, Shanghai Municipality, China

Sichuan Provincial People's Hospital

Chengdu, Sichuan, China

View Full Details on ClinicalTrials.gov

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NCT07597200

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