RecruitingEarly Phase 1NCT07598695

Sensory Feedback and Hand Motor Adaptation

Impact of Altered Sensory Feedback on Adaptation of Hand Muscle Coordination of Stroke Survivors


Sponsor

The Catholic University of America

Enrollment

30 participants

Start Date

Oct 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The following experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform hand movements in the virtual reality environment using a head-mounted display. Quest's onboard cameras allow real-time tracking of hand motion, estimating joint angles of the finger and the thumb. For each feedback manipulation condition (i.e., movement amplification or reduction), the estimated joint angles will be multiplied by a factor greater than 1 (amplification) or a factor smaller than 1 (reduction). Then the newly-estimated hand posture will be displayed in the VR environment. Subjects will be randomly assigned into two groups (A and B), who will receive the assistance in a different order. Subjects will perform finger extension under three conditions: no sensory modulation, movement visual feedback (VF) amplification, and movement VF reduction (error augmentation), while their movement muscle activation patterns are recorded.


Eligibility

Min Age: 20 YearsMax Age: 70 Years

Inclusion Criteria3

  • Age: 20 - 70 years old
  • First-ever unilateral cortical stroke with resultant hemiparesis at least 6 months prior to the experimental testing
  • Fugl-Meyer Upper Extremity Section 31 - 55

Exclusion Criteria5

  • Presence of concurrent severe medical illness
  • Pain in hand or arm with movements
  • Loss of voluntary control of fingers and thumb
  • Inability to provide informed consent
  • Musculoskeletal injuries (e.g., fracture) or medical complications (e.g., severe cardiovascular disease).

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICEVisual ROM augmentation

Finger joint ROM is amplified.

DEVICEVisual ROM reduction

Visual feedback of finger joint ROM is reduced.


Locations(1)

Catholic University of America

Washington D.C., District of Columbia, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07598695


Related Trials