RecruitingNot ApplicableNCT07606573

The SEAS Study: Sensory Engagement and Activation During Noninvasive Stimulation


Sponsor

University of Minnesota

Enrollment

40 participants

Start Date

Jun 8, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Early feasibility study to establish quantitative physiological markers correlated with noninvasive stimulation.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria2

  • Able to provide written informed consent in English.
  • Willing and able to complete study procedures (e.g., ~1-hour sessions with non-invasive recordings, ~3-hour visit).

Exclusion Criteria6

  • History of neurological disorders (e.g., epilepsy, migraines) or psychiatric conditions requiring medication.
  • Active implanted medical devices (e.g., pacemakers, cochlear implants) or metal in the neck/forearm that could interfere with stimulation or recordings.
  • Skin conditions or open wounds at stimulation sites (cervical neck, forearm).
  • Women who are pregnant or breastfeeding.
  • Current use of medications affecting autonomic or cortical function (e.g., beta-blockers, sedatives).
  • Inability to sit still for recordings or understand instructions (e.g., due to severe vision/hearing impairment).

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Interventions

DEVICEExternal electrical stimulation

Electrical stimulation

DEVICEUltrasound stimulation

USS


Locations(3)

M Health Clinical Research Unit

Minneapolis, Minnesota, United States

M Health Clinics and Surgery Center and satellite Neurology Clinic locations

Minneapolis, Minnesota, United States

Translational Neurotechnology (TNT) Lab

Minneapolis, Minnesota, United States

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NCT07606573


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