RecruitingPhase 2NCT07610473

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

A Phase 2 Double-blind, Randomised, Placebo-controlled Trial to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of DT-101 in Adults With Major Depressive Disorder Receiving Pharmacological Therapy for Depression


Sponsor

Draig Therapeutics Ltd

Enrollment

118 participants

Start Date

Jun 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

In this study, researchers will learn more about a study drug called DT-101 in participants with Major Depressive Disorder (MDD), a form of depression. The goal of this clinical trial is to learn if DT-101 can treat depression in adults. The effect of DT-101 will be compared to placebo. A placebo looks the drug but contains no medicine. Subjects will attend the clinic for complete general health checks and to complete questionnaires.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called DT-101 and a drug called Placebo for people with major depressive disorder (mdd). The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDT-101

DT-101

DRUGPlacebo

Placebo


Locations(11)

Draig Clinical Site

Phoenix, Arizona, United States

Draig Clinical Site

Little Rock, Arkansas, United States

Draig Clinical Site

Lafayette, California, United States

Draig Clinical Site

Hialeah, Florida, United States

Draig Clinical Site

Tampa, Florida, United States

Draig Clinical Site

Decatur, Georgia, United States

Draig Clinical Site

Chicago, Illinois, United States

Draig Clinical Site

New York, New York, United States

Draig Clinical Site

New York, New York, United States

Draig Clinical Site

Media, Pennsylvania, United States

Draig Clinical Site

DeSoto, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT07610473


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