RecruitingPhase 2NCT07625891

Study of D-2570 in Subjects With Non-Segmental Vitiligo

A Phase 2 Multicenter, Randomized, Parallel-group, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of D-2570 in Subjects With Non-Segmental Vitiligo


Sponsor

InventisBio Co., Ltd

Enrollment

160 participants

Start Date

Jun 11, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study tests D-2570, an investigational drug, in people with non-segmental vitiligo to check its safety and effect on skin discoloration. Eligible participants will take D-2570, or a placebo, once daily for 24 weeks in a double-blind setting. Most will then continue into a 24-week extension phase All participants will have a 4-week safety follow-up after treatment ends, with regular check-ups and blood tests throughout the study.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called D-2570 Dose 1, a drug called D-2570 Dose 2, and others for people with non-segmental vitiligo (nsv) and vitiligo. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGD-2570 Dose 1

Oral D-2570 Dose 1 administered once daily for 24 weeks during the double-blind treatment period. Eligible subjects may continue the same dose in the 24-week extension period

DRUGD-2570 Dose 2

Oral D-2570 Dose 2 administered once daily for 24 weeks during the double-blind treatment period. Eligible subjects may continue the same dose in the 24-week extension period.

DRUGPlacebo

Oral placebo administered once daily for 24 weeks during the double-blind treatment period. Subjects will be re-randomized to D-2570 Dose 1 or Dose 2 in the extension period.

DRUGD-2570 Dose 3

Oral D-2570 Dose 3 administered once daily for 24 weeks during the double-blind treatment period. Subjects will be re-randomized to D-2570 Dose 1 or Dose 2 in the extension period.


Locations(1)

Huashan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

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NCT07625891


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