RecruitingNot ApplicableNCT07626736

Evaluating the Efficacy and Safety of AI Localization Models in Multidisciplinary Team Care for NSCLC

Evaluating the Efficacy and Safety of AI Localization Models in Multidisciplinary Team Care for NSCLC: a Prospective, Controlled Clinical Trial Protocol


Sponsor

Wen-zhao ZHONG

Enrollment

300 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to evaluate the effectiveness and safety of a locally deployed artificial intelligence (AI) decision-support model in the multidisciplinary team (MDT) process for patients with non-small cell lung cancer (NSCLC). The main questions it aims to answer : What is the level of agreement between treatment recommendations generated by the AI model and those made by a traditional MDT? How often do clinicians modify their final treatment decision after reviewing the AI model's recommendation? Researchers will compare treatment plans from the traditional MDT (Arm 1), the AI model (Arm 2), and the clinician's final decision after reviewing the AI output (Arm 3) to assess consistency, decision modification rates, and clinical efficiency. Participants will: Have their clinical, imaging, and molecular data submitted to both the traditional MDT and the AI model for independent treatment recommendations Receive a final treatment plan determined by clinicians after reviewing both recommendations, with follow-up for safety and survival outcomes


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Age ≥ 18 years;
  • MDT (Multidisciplinary Team) discussion deems a systemic treatment plan necessary;
  • Complete clinical, imaging, and molecular pathological data.

Exclusion Criteria3

  • Stage I patients;
  • Diagnosed with a thoracic tumor other than NSCLC;
  • Lack of detailed medical data, or missing data;

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Interventions

DIAGNOSTIC_TESTTreat Regimen

The impact of artificial intelligence on clinicians' treatment plans


Locations(1)

Guangdong Provincial People's Hospital

Guangzhou, Guangdong, China

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NCT07626736


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