RecruitingNot ApplicableNCT07629479

Ejaculation-Preserving Versus Standard Bipolar TUEP for BPH

Bipolar Transurethral Enucleation of the Prostate With Preservation of Ejaculation in Patients With Benign Prostatic Hyperplasia: A Randomized Controlled Trial

Sponsor

Beni-Suef University

Enrollment

60 participants

Start Date

Sep 8, 2025

Study Type

INTERVENTIONAL

Conditions

Benign Prostatic Hyperplasia Lower Urinary Tract Symptoms Benign Prostatic Obstruction

Summary

This prospective randomized controlled trial will compare ejaculation-preserving bipolar transurethral enucleation of the prostate with standard bipolar transurethral enucleation of the prostate in sexually active men with benign prostatic hyperplasia and lower urinary tract symptoms after failed medical treatment. Participants will be randomly assigned to either ejaculation-preserving B-TUEP or standard B-TUEP. The study will evaluate preservation of ejaculatory function, erectile function, urinary symptom improvement, uroflowmetry outcomes, post-void residual urine, perioperative complications, and need for retreatment during follow-up.

Eligibility

Sex: MALEMin Age: 50 Years

Inclusion Criteria7

Male patients with lower urinary tract symptoms secondary to benign prostatic obstruction after failed medical treatment for at least 3 months.
Sexually active patients with a continuous relationship with the same partner.
International Prostate Symptom Score of 8 or greater.
Transrectal ultrasound-estimated prostate size between 40 and 100 cc.
Eligible for bipolar transurethral enucleation of the prostate.
Ability to complete the required sexual and urinary function questionnaires.
Ability to provide written informed consent.

Exclusion Criteria8

Preoperative sexual dysfunction.
Preoperative ejaculatory dysfunction.
Diagnosis or suspicion of prostate cancer.
Neurological disorders affecting lower urinary tract or sexual function.
Detrusor hypocontractility.
Catheter-dependent patients.
Patients with bladder stones.
Inability or refusal to provide informed consent.

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Interventions

PROCEDUREEjaculation-Preserving Bipolar Transurethral Enucleation of the Prostate

Ejaculation-preserving bipolar transurethral enucleation of the prostate will be performed with preservation of the paracollicular tissue, the area approximately 1 cm proximal to the verumontanum, and bladder neck fibers, while avoiding deep enucleation behind the verumontanum.

PROCEDUREStandard Bipolar Transurethral Enucleation of the Prostate

Standard bipolar transurethral enucleation of the prostate will be performed according to the conventional surgical technique without preservation of the paracollicular tissue and the area approximately 1 cm proximal to the verumontanum.