Comparison of Double-tract and Tubular Gastric Anastomosis in Proximal Gastric Cancer
Comparison of Gastroesophageal Reflux and Quality of Life Between Double-tract and Tubular Gastric Anastomosis in Proximal Gastric Cancer Patients
Qilu Hospital of Shandong University
52 participants
May 1, 2026
INTERVENTIONAL
Conditions
Summary
This study includes patients diagnosed with proximal gastric cancer (Siewert type II/III, cT1-3N0-1M0) across six tertiary hospitals, who underwent either double-tract reconstruction (DTR) or tubular gastric anastomosis (TGA). Participants were divided into two groups based on the surgical procedure. We conducted a comparative analysis of postoperative outcomes by evaluating electronic medical records, postoperative gastroscopy, 24-hour esophageal pH monitoring, and relevant rating scales.
Eligibility
Inclusion Criteria5
- Pathologically confirmed gastric adenocarcinoma by biopsy
- Carcinoma of the upper gastric body or Siewert type II/III adenocarcinoma of the esophagogastric junction (AEG), with a clinical stage of cT1-3N0-1M0
- Age 18-75 years, with a performance status (PS) score of 0-2
- Candidates for planned surgical resection, eligible for either double-tract reconstruction or tubular gastric anastomosis based on preoperative assessment
- No severe dysfunction of vital organs (liver, kidney, heart, lung, or brain), and no severe infection or uncontrolled chronic diseases
Exclusion Criteria6
- Presence of other malignant tumors or severe chronic diseases (e.g., severe diabetes mellitus, chronic kidney disease, decompensated cirrhosis, etc.)
- Preoperative endoscopic diagnosis of Barrett's esophagus
- Severe preoperative malnutrition (albumin <30 g/L, prealbumin <150 mg/L)
- History of prior upper abdominal surgery, gastrointestinal malformation, or psychiatric disorders
- Preoperative diagnosis of obstructive motor disorders of the cardia (including achalasia spectrum disorders)
- Inability to cooperate with or complete the required postoperative examinations
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Interventions
Patients underwent double-tract reconstruction after radical proximal gastrectomy
Locations(1)
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NCT07635836