RecruitingNot ApplicableNCT07637266

Impact of Del Nido Versus Blood Cardioplegia on Myocardial Viability Assessed With Magnetic Resonance Imaging


Sponsor

Klinički Bolnički Centar Zagreb

Enrollment

60 participants

Start Date

Jun 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Myocardial protection during surgical myocardial revascularization is crucial for reducing perioperative myocardial injury and improving postoperative outcomes. Blood cardioplegia represents the standard method in many centers, while del Nido cardioplegia, originally developed for the pediatric population, is increasingly being used in adult patients as well.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria2

  • Eligibility Criteria:
  • \. Patients with multivessel coronary artery disease scheduled for elective coronary artery bypass grafting

Exclusion Criteria5

  • Left ventricular ejection fraction <30%
  • Associated cardiac procedures
  • Off-pump coronary artery bypass grafting
  • Contraindications for MRI
  • Inability to provide consent

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Interventions

DRUGDel Nido Cardioplegia Solution for myocardial protection

CABG patients receiving Del Nido cardioplegia as the myocardial protection strategy

DRUGBlood Cardioplegia Solution for myocardial protection

Patients will receive Blood Cardioplegia Solution for myocardial protection


Locations(2)

University Hospital Center Zagreb

Zagreb, Croatia

University Hospital Center Zagreb

Zagreb, Croatia

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NCT07637266


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