Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open Nephrectomy
Ultrasound Guided Rhomboid Intercostal Sub-serratus Plane Block Versus External Oblique Intercostal Block in Open Nephrectomy: Randomized Controlled Study
Cairo University
90 participants
May 2, 2026
INTERVENTIONAL
Conditions
Summary
This study aims to compare time of first request of analgesia among patients undergoing rhomboid intercostal sub-serratus plane block versus external oblique intercostal block for perioperative pain management in open nephrectomy.
Eligibility
Inclusion Criteria4
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status II, III.
- Body mass index (BMI): > 20 kg/ m2 and < 35 kg/ m2.
- Patients undergoing open nephrectomy.
Exclusion Criteria10
- Patient refusal.
- BMI <20 kg/m2 and >35 kg/m2
- Known sensitivity or contraindication to drug used in the study (local anesthetics, opioids).
- History of psychiatric and cognitive disorders or chronic pain.
- Contraindication to regional anesthesia e.g pre- existing peripheral neuropathies.
- Severe respiratory or cardiac disorders.
- Advanced liver or kidney disease.
- Pregnancy.
- Physical status ASA IV.
- Coagulopathy with INR ≥ 1.6: hereditary (e.g. hemophilia, fibrinogen abnormalities \& deficiency of factor II) - acquired (e.g. impaired liver functions with prothrombin concentration less than 60 %, vitamin K deficiency \& therapeutic anticoagulants drugs).
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Interventions
Patients will receive the rhomboid intercostal subserratus plane block.
Patients will receive the external oblique intercostal block.
Patients will not receive any interventions (Intravenous morphine 0.1mg/kg after induction of general anesthesia).
Locations(1)
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NCT07642193