RecruitingNot ApplicableNCT07642856
Individualized Neuro-Modulation Paired With Cerebellar Therapy
Sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Enrollment
30 participants
Start Date
Jun 30, 2026
Study Type
INTERVENTIONAL
Conditions
Summary
The purpose of this project is to evaluate feasibility and preliminary efficacy of pairing personalized transcranial direct current stimulation (tDCS) with individualized rehabilitation therapy in people with cerebellar damage.
Eligibility
Min Age: 18 YearsMax Age: 75 Years
Inclusion Criteria3
- Age 18-75 years
- Males and Females
- Disorders that predominantly affect the cerebellum: damage from stroke, tumor or degeneration (genetic or non-genetic causes, congenital hypoplasia).
Exclusion Criteria11
- Diagnoses or impairments that interfere with task execution or data interpretation.
- Heart pacemaker or other MRI-incompatible implanted metal device
- Metallic foreign body in their eye or head
- Experience with severe claustrophobia
- Experience discomfort from the MRI scan, such as excessive heating of tattoos
- Seizures or history of seizure disorder
- Alcohol or substance use disorder (self-report)
- Diagnosed history of severe psychiatric disorder such as depression, schizophrenia (self-report)
- Metallic foreign body in their eye or head (except the mouth e.g. dental fillings)
- Specific medications: tricyclic anti-depressants or neuroleptic medication
- Any medical condition (including orthopedic, pain, cardiopulmonary or other) that limits safe participation in exercise training
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
BEHAVIORALTherapy
Each participant will choose a domain that they would like to focus on. Choices are: 1) walking and balance control, 2) hand dexterity and arm control, or 3) speech articulation, prosody, and intelligibility.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07642856
Related Trials
Retraining Reaching in Cerebellar Ataxia
NCT038790181 location
Enhancement of Quality of Work And Life
NCT065738661 location
Evaluation of Urinary Dysfunction in CANVAS Patients
NCT068177073 locations
Home Exercise for Individuals with Neurodegenerative Disease
NCT054439061 location
A Registered Cohort Study on Cerebellar Ataxia in the Organization in South-East China for Cerebellar Ataxia Research (OSCCAR)
NCT040102141 location