RecruitingPhase 2NCT07646860

A Study of Sotatercept (MK-7962) in Japanese Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-032)

A Phase 2 Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Sotatercept (MK-7962) in Japanese Children From 1 to Less Than 18 Years of Age With PAH on Standard of Care.


Sponsor

Merck Sharp & Dohme LLC

Enrollment

6 participants

Start Date

Sep 25, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to learn about the safety of sotatercept and how well Japanese children tolerate it, when taken along with standard (usual) pulmonary arterial hypertension (PAH) treatment. Researchers also want to learn what happens to it in a person's body over time and whether it lowers resistance in blood vessels in the lungs.


Eligibility

Min Age: 1 YearMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Sotatercept for people with pulmonary arterial hypertension. The study is currently recruiting participants at 1 location. People eligible for this study include aged 1 Year to 17 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALSotatercept

Sotatercept subcutaneous injection every 3 weeks


Locations(3)

Osaka Prefectural Hospital Organization Osaka Women's and Children's Hospital ( Site 3203)

Izumi, Osaka, Japan

The University of Osaka Hospital ( Site 3201)

Suita, Osaka, Japan

National Center for Child Health and Development ( Site 3202)

Setagaya City, Tokyo, Japan

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NCT07646860


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