RecruitingPhase 2NCT07648030

A Study of Rusfertide in Japanese Adults With Polycythemia Vera

A Phase 2 Open-label Trial to Evaluate the Efficacy and Safety of Rusfertide in Japanese Patients With Polycythemia Vera


Sponsor

Takeda

Enrollment

9 participants

Start Date

Jul 14, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Polycythemia vera (PV) is a rare blood cancer in which the body makes too many red blood cells. This can make the blood thicker and may increase the risk of serious health problems such as blood clots. Many people with PV need regular phlebotomy, which is a procedure to remove blood, to help keep their hematocrit level under control. Hematocrit is the proportion of red blood cells in the blood. The main aim of this study is to evaluate whether rusfertide helps Japanese participants with PV keep their hematocrit under control and avoid the need for phlebotomy. All participants in this study will receive rusfertide. This study is open-label, which means both the participants and the study team will know what treatment is being given. Participants will be followed for up to about 244 weeks, including a screening period, a 52-week initial treatment period, a long-term extension period, and a 4-week safety follow-up period.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Rusfertide for people with polycythemia vera. The study is currently recruiting participants at 4 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGRusfertide

Rusfertide injections administered subcutaneously.


Locations(4)

Mie University Hospital

Tsu, Mie-ken, Japan

University of Osaka Hospital

Suita, Osaka, Japan

Juntendo University Hospital

Bunkyo-ku, Tokyo, Japan

University of Yamanashi Hospital

Chūō, Yamanashi, Japan

View Full Details on ClinicalTrials.gov

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NCT07648030


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