RecruitingNCT07652580

Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma

Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma Across the Military Healthcare System

Sponsor

Henry M. Jackson Foundation for the Advancement of Military Medicine

Enrollment

300 participants

Start Date

May 1, 2025

Study Type

OBSERVATIONAL

Conditions

Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin Immune Dysregulation B-cell Lymphoma

Summary

The goal of this observational cohort study is to learn how toxin and occupational exposures, germline genetic variation, and immune dysregulation relate to B-cell non-Hodgkin lymphoma among active-duty service members and other Military Health System beneficiaries. The main questions are whether specific exposures and germline variants are associated with B-cell NHL subtype, immune dysfunction, and clinical outcomes. Participants will complete exposure and medical-history surveys, provide biospecimens for immune and genomic testing, and may be followed annually for up to 3 years.

Eligibility

Min Age: 4 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with b-cell lymphoma, immune dysregulation, and other related conditions. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 4 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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