RecruitingPhase 4NCT07652684

Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants

Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants: A Randomized Controlled Trial (The PRELUDE Trial)

Sponsor

Aristotle University Of Thessaloniki

Enrollment

74 participants

Start Date

Mar 4, 2025

Study Type

INTERVENTIONAL

Conditions

Bronchopulmonary Dysplasia (BPD)

Summary

The Impact of Omega-3 (DHA - Docosahexaenoic Acid) and Omega-6 (ARA - Arachidonic Acid) Supplementation on the Development of Bronchopulmonary Dysplasia in Extremely and Very Preterm Infants (24-29 weeks of gestational age).

Eligibility

Min Age: 24 WeeksMax Age: 29 Weeks

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Enteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding and Standard care and feeding for people with bronchopulmonary dysplasia (bpd). The study is currently recruiting participants at 1 location. People eligible for this study include aged 24 Weeks to 29 Weeks.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTEnteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding

The intervention group will receive enteral supplementation containing arachidonic acid (ARA) and docosahexaenoic acid (DHA) in a 2:1 ratio, in addition to standard care and feeding. Supplementation will begin within the first three days of life and will continue until 36 weeks postmenstrual age.

OTHERStandard care and feeding

The control group will receive routine clinical care and nutritional support according to current neonatal unit protocols, without additional ARA/DHA supplementation.

Locations(1)

Papageorgiou General Hospital

Thessaloniki, Greece

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NCT07652684

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