RecruitingPhase 3NCT07661758

Intravenous Lidocaine to Prevent Post-Fundal Pressure Headache During Cesarean Section

Pre-emptive Single Intravenous Lidocaine Dose to Prevent Post-Fundal Pressure Headache During Cesarean Section: The LID-HEAD Multi-center Randomized Controlled Trial


Sponsor

Tanta University

Enrollment

680 participants

Start Date

Jul 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective randomized controlled multicenter study will be conducted to evaluate the effects of pre-emptive IV lidocaine dose on the incidence and severity of intraoperative headache that may occur after the extra-abdominal manual uterine fundal pressure in patients undergoing cesarean section under spinal anesthesia.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Lidocaine IV and Saline 0.9% for people with fundal pressure, headache, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLidocaine IV

IV lidocaine 1.5 mg/kg (diluted with 0.9% isotonic saline to a total volume of 10 ml) over 5 minutes with the start of skin incision after ensuring negative baseline headache.

OTHERSaline 0.9%

IV 10 ml isotonic saline over 5 minutes with the start of skin incision after ensuring negative baseline headache.


Locations(1)

Tanta University Hospitals

Tanta, Gharbia Governorate, Egypt

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NCT07661758


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