RecruitingNCT07663669

Use of Extracorporeal Photopheresis in Kidney Transplantation: Effects on Antibody-Mediated Rejection


Sponsor

Centre Hospitalier Universitaire de Besancon

Enrollment

31 participants

Start Date

Jun 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to describe, over a one-year period, the clinical, biological, and histological evolution of a cohort of kidney transplant recipients who developed antibody-mediated rejection and were treated with extracorporeal photopheresis.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Kidney transplant recipients followed at the University Hospitals of Besançon and Lille between September 1, 2016, and August 31, 2023
  • Patients with antibody-mediated rejection (as confirmed by histological analysis of the renal biopsy)
  • Rejection treated with extracorporeal photopheresis
  • Subjects who do not object to the use of their personal data and/or biological samples
  • Subjects affiliated with, or beneficiaries of, the French social security system

Exclusion Criteria7

  • Patients with acute rejection
  • Pregnant women, women in labor, or breastfeeding mothers
  • Individuals deprived of liberty by judicial or administrative decision; individuals receiving compulsory psychiatric care; or individuals admitted to a healthcare or social institution for reasons other than research participation
  • Minors
  • Adults under legal protection or unable to provide informed consent
  • Subjects without health insurance coverage
  • Subjects currently within an exclusion period from another study, or as listed in the "national volunteer registry"

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Locations(1)

Centre Hospitalier Universitaire de Besançon

Besançon, France

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NCT07663669