RecruitingPhase 2NCT07669415

A Study of LM-168 Combined With Other Anti-tumor Treatments in Participants With Advanced Solid Tumors

A Phase II,Open Label,Multicenter Study to Evaluate the Efficacy,Safety,and Tolerability of LM-168 Combined With Other Anti-tumor Therapies in Participants With Advanced Solid Tumor Trials


Sponsor

LaNova Medicines Limited

Enrollment

108 participants

Start Date

Jul 29, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

For Safety introduction phase,this study is to evaluate the safety and tolerability of LM-168 in combination with other anti-tumor treatment regimens in participants of advanced solid tumor trials, determine the maximum tolerated dose (MTD), and explore the recommended phase II dose (RP2D). For Dose expansion phase,this study is to evaluate the preliminary antitumor activity of LM-168 in combination with other antitumor treatment regimens in participants of advanced solid tumor trials, measured by objective response rate (ORR)


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Docetaxel injection, a drug called LM-168, and others for people with advanced solid tumor. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLM-168

Q3W,Intravenous Drip

DRUGTislelizumab

Q3W,Intravenous Drip

DRUGDocetaxel injection

Q3W,Intravenous Drip


Locations(1)

Peking University Cancer Hospital

Beijing, Beijing Municipality, China

View Full Details on ClinicalTrials.gov

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NCT07669415


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