RecruitingPhase 1NCT07669571

A Phase I Study of NS-079 in Healthy Participants

A Phase I, Double-blind, Placebo-controlled Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of NS-079 in Healthy Participants


Sponsor

NeuShen Therapeutics

Enrollment

78 participants

Start Date

Jul 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is evaluate the safety, pharmacokinetics, and pharmacodynamics of NS-079 with its main metabolite (NS-079-M1) in healthy participants. The main questions it aims to answer are: * Is NS-079 safe and tolerable in heathy participants under tested dosing regimen? * What is the pharmacokinectic profile of NS-079 in healthy participants under tested dosing regimen and the effect of paroxetine? Researchers will compare NS-079 to a placebo to see the safety and tolerability when use NS-079.


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called NS-079 tablet, a drug called Paroxetine, and others for people with healthy adult participants. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPlacebo

NS-079 matching placebo

DRUGNS-079 tablet

Investigational product NS-079

DRUGParoxetine

DDI study treatment drug


Locations(1)

CMAX Clinical Research Pty Ltd

Adelaide, South Australia, Australia

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NCT07669571


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