RecruitingPhase 2NCT07673744

A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)

A Phase 2, Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Treatment Following Induction With Efgartigimod Administration in Adults With Myasthenia Gravis


Sponsor

TG Therapeutics, Inc.

Enrollment

120 participants

Start Date

Jul 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The primary purpose of this study is to evaluate the efficacy of ublituximab in adult participants with MG responding to treatment with efgartigimod.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called Ublituximab for people with myasthenia gravis. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGUblituximab

Administered as an IV infusion.

DRUGPlacebo

Administered as an IV infusion.


Locations(2)

TG Therapeutics Investigational Trial Site

Colorado Springs, Colorado, United States

TG Therapeutics Investigational Trial Site

Clearwater, Florida, United States

View Full Details on ClinicalTrials.gov

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NCT07673744


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