RecruitingNCT07680699

NEOSENT: Early Anti-PD-1 Therapy In High-Risk Stage II Melanoma

NEOSENT - Early Anti-PD-1 Therapy In Patients With High-Risk Stage II Melanoma And/Or Microsatellitosis: An Ambispective Observational Cohort Study


Sponsor

AC Camargo Cancer Center

Enrollment

250 participants

Start Date

Apr 23, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This is an observational cohort study evaluating clinical and pathological outcomes in patients with high-risk stage II melanoma. Patients are included after receiving treatment as part of routine clinical practice. Decisions about treatment, including whether to start anti-PD1 therapy before surgery, are made by the treating physician and are not influenced by the study. The study compares outcomes between patients who started anti-PD1 therapy before surgery and those treated according to the usual timing in clinical practice. No treatments are assigned as part of the study.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Anti-PD1 Therapy Timing for people with cutaneous melanoma. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERAnti-PD1 Therapy Timing

This is an observational study variable. The timing of anti-PD1 therapy initiation in relation to surgery is determined by the treating physician as part of routine clinical practice. The study does not assign or modify any treatment.


Locations(1)

AC Camargo Cancer Center

São Paulo, São Paulo, Brazil

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NCT07680699


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