RecruitingNCT07683962

Influence of Early Wound Healing on the Outcomes of Regenerative Periodontal Surgery

Influence of Early Wound Healing on the 12-month Clinical and Radiographic Outcomes of Regenerative Periodontal Surgery: a Prospective Observational Cohort Study

Sponsor

University of Roma La Sapienza

Enrollment

100 participants

Start Date

Jul 1, 2026

Study Type

OBSERVATIONAL

Conditions

Wound Healing Intrabony Periodontal Defect

Summary

This study investigates whether early post-surgical healing (1-2 weeks) affects the 12-month clinical and radiographic success of periodontal regenerative therapy, and identifies patient-related, site-specific, and technique-related factors associated with optimal early wound healing, in patients with Stage III-IV periodontitis.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Periodontal Regenerative Therapy for people with intrabony periodontal defect and wound healing. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPeriodontal Regenerative Therapy

All subjects undergo surgical debridement of the intrabony defect followed by a regenerative approach (biologics with or without bone grafts, or blood clot alone) using papilla preservation techniques (MIST, M-MIST, MPPT, SPPF, or SFA).

Locations(1)

Sapienza University of Rome, Department of Oral and Maxillofacial Sciences, Section of Periodontology

Rome, Rome, Italy

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NCT07683962

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