Placental Progesterone Membrane Receptors in Fetal Growth Restriction

This prospective observational case-control study aims to compare placental expression levels of progesterone membrane receptors, including PGRMC1, PGRMC2, and PAQR family receptors, between pregnancies complicated by intrauterine growth restriction (IUGR) and uncomplicated healthy pregnancies. Placental tissue samples obtained at delivery will be analyzed using quantitative real-time polymerase chain reaction (qRT-PCR). The study also aims to investigate the association between receptor expression levels and perinatal outcomes in order to better understand the role of progesterone membrane receptors in the pathophysiology of IUGR.