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RecruitingPhase 1NCT07709286

Clinical Efficacy of Antivet Versus Phosphoric Acid and Hydrochloric Acid in Microabrasion

Clinical Efficacy of Antivet Versus Phosphoric Acid and Hydrochloric Acid in Microabrasion Technique for Treatment of Stained Teeth: Randomized Clinical Trial

Sponsor

Misr University for Science and Technology

Enrollment

60 participants

Start Date

Jan 10, 2026

Study Type

INTERVENTIONAL

Conditions

Teeth Staining

Summary

This clinical trial will be conducted to assess the clinical efficacy of using Antivet cleaning enamel solution or hydrochloric acid and phosphoric acid in microabrasion technique for mild to moderate intrinsic stained teeth.

Eligibility

Min Age: 16 YearsMax Age: 50 Years

Inclusion Criteria8

  • Eligibility Criteria of participants:
  • Patients with moderate to mild stained teeth.
  • -50 years.
  • Males or Females.
  • Co-operative patients approving to participate in the study.
  • Anterior teeth.
  • Mild to moderate intrinsic or extrinsic stains.
  • Vital and non-sensitive anterior teeth.

Exclusion Criteria12

  • High caries index with poor oral hygiene.
  • Severe medical complications.
  • Pregnancy.
  • Xerostomia.
  • Lack of compliance.
  • Smokers
  • Eligibility Criteria of teeth:
  • pitted enamel.
  • carious teeth.
  • Deep lesions.
  • Severe periodontal problems.
  • Previous treatment for the stained teeth

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Interventions

DRUG(Antivet, MDC DENTAL, Zapopan Jalisco México)

specially formulated to eliminate stains on the enamel surface caused by dental fluorosis or any other external factor.The tooth's surface is exposed to an acid solution by ionization by the fluoride absorbed in the apatite crystals (stains). This reaction allows for the fluoride ions to separate from the fluoride ions in the apatite crystals, forming soluble salts that are easily removed from the tooth enamel surface. Once the stains are removed, a calcium hydroxide solution is applied to neutralize the residual acidic solution left on the tooth surface. Lastly, the tooth is rinsed with water.Acid Base (Antivet): It is hydrofluoric acid at a 21% concentration stabilized by an organic tricarboxylic acid, with a controlled pH of \<3, necessary to react with the fluoride ions to form soluble salts. The organic and inorganic ions are extracted from within the fluorapatite crystals through this ionization process which essentially allows the enamel surface to be cleansed without damaging it

DRUGOpalustre

technique involves employing a mixture 6.6% hydrochloric acid with silica carbide particles, with rubber cup in slow rotating motion to the areas of discoloration or white opacities for 60 seconds. The teeth will be rinsed with water between slurry applications. Depending on the stain reduction, microabrasion will be repeated up to six times during the same appointment to achieve the desired result. .

DRUGphosphoric acid 37% and aluminium oxid 50 microns

● Equal quantities from phosphoric acid 37% and aluminium oxid 50 microns will be mixed, thick mix will be applied on the affected tooth/teeth and will be rubbed with a rubber cup in a low-speed contra-angle handpiece for 60 seconds of each application. Every patient will be received the entire microabrasion treatment in a single appointment with a maximum of 6 applications.

Locations(1)

Egyptian Russian University

Badr, Cairo Governorate, Egypt

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NCT07709286