TCP-600 Supplementation and Performance Response in Professional Football Players
External Validation and Extension of Physical, Recovery, and Perceptual-Cognitive Responder Profiles After Phosphatidylserine-Containing Taurine-Caffeine Supplementation in Professional Football Players: A Randomized, Double-Blind, Placebo-Controlled Trial
Vizja University in Warsaw
65 participants
Sep 1, 2026
INTERVENTIONAL
Conditions
Summary
This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function, recovery-related readiness, and selected football-specific perceptual-cognitive performance. Participants will be randomly assigned to receive either placebo or a phosphatidylserine-containing multi-ingredient supplement. Before and after the supplementation period, players will complete non-invasive assessments such as sprint testing, reaction-time testing, heart rate variability monitoring, wellness/readiness questionnaires, mental-fatigue measures, and selected football-specific perceptual-cognitive tasks where available. The study is designed as an external validation and extension of responder profiles derived from previous randomized controlled trials. Data from previous trials and this validation cohort will be used to examine whether baseline physical, cognitive, autonomic, fatigue-related, recovery-related, or perceptual-cognitive characteristics can predict which players are most likely to benefit from phosphatidylserine-containing multi-ingredient supplementation.
Eligibility
Plain Language Summary
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Interventions
Matching placebo capsules administered orally once daily for 28 consecutive days. The placebo was matched to the active supplements in appearance, number, packaging, and administration schedule.
Taurine 1500 mg/day administered orally once daily in capsules for 28 consecutive days.
Anhydrous caffeine 200 mg/day administered orally once daily in capsules for 28 consecutive days.
Phosphatidylserine 600 mg/day administered orally once daily in capsules for 28 consecutive days.
Locations(3)
View Full Details on ClinicalTrials.gov
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NCT07710547