RecruitingNCT07717255

Adequacy of Haemodiafiltration: Middle Molecules Clearance, Patients Reported Outcomes and Sodium Balance


Sponsor

East and North Hertfordshire NHS Trust

Enrollment

300 participants

Start Date

Jan 9, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to understand the differences in terms of middle molecules clearance and patient outcomes in High (\>23Litres (L)) vs Low (\<23 L) convection volume (CV) Hemodiafiltration (HDF) and to understand the effect of dialysate fluid sodium concentration (137 vs 140 mmol/L) on overhydration volume in patients on HD and HDF.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age 18 years or above.
  • Ability to give informed consent.
  • End stage kidney disease (ESKD) treated by haemodialysis for at least 3 months.
  • Prognosis > 6 months as assessed by principal investigator (PI)

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Locations(1)

Lister Hospital, East and North Hertfordshire NHS Trust

Stevenage, Hertfordshire, United Kingdom

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NCT07717255


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