RecruitingNot ApplicableNCT07717463

Pericapsular Nerve Group Block Versus Femoral Nerve Block Study

Comparison of Preoperative Pericapsular Nerve Group (PENG) Block Versus Femoral Nerve Block for Optimizing Spinal Anaesthesia in Proximal Femur Fracture Surgery: A Prospective Randomized Controlled Trial


Sponsor

Taksim Egitim ve Arastirma Hastanesi

Enrollment

110 participants

Start Date

Jul 22, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Hip fractures are common in older adults and are often associated with severe pain, making it difficult for patients to sit for spinal anesthesia before surgery. Peripheral nerve blocks may improve pain control and facilitate patient positioning, but it remains uncertain whether the Pericapsular Nerve Group (PENG) block provides advantages over the traditional femoral nerve block during the spinal anesthesia procedure.


Eligibility

Min Age: 50 Years

Inclusion Criteria5

  • Adults aged 50 years or older.
  • Diagnosis of proximal femoral fracture.
  • Scheduled to undergo surgical repair under spinal anesthesia.
  • American Society of Anesthesiologists (ASA) physical status I-III.
  • Able to provide written informed consent.

Exclusion Criteria10

  • Refusal to participate or inability to provide informed consent.
  • Coagulopathy or contraindication to spinal anesthesia or peripheral nerve block.
  • Local infection at the planned injection site.
  • Known allergy or hypersensitivity to local anesthetics.
  • Pre-existing neurological disease affecting lower extremity function or sensory assessment.
  • Cognitive impairment preventing reliable study participation or outcome assessment.
  • Previous lumbar spine surgery.
  • Polytrauma.
  • Body mass index (BMI) <18 kg/m² or >40 kg/m².
  • Current anticoagulant therapy that precludes neuraxial anesthesia or peripheral nerve block according to institutional practice.

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Interventions

PROCEDUREUltrasound-Guided Pericapsular Nerve Group (PENG) Block

Ultrasound-guided PENG block performed before spinal anesthesia using 20 mL of 0.25% bupivacaine to provide analgesia for patients undergoing surgery for proximal femur fracture.

PROCEDUREUltrasound-Guided Femoral Nerve Block

Ultrasound-guided femoral nerve block performed before spinal anesthesia using 20 mL of 0.25% bupivacaine to provide analgesia for patients undergoing surgery for proximal femur fracture.

PROCEDURESpinal Anesthesia (bupivacaine)

Standard spinal anesthesia performed after the assigned peripheral nerve block using intrathecal hyperbaric bupivacaine according to the study protocol.


Locations(2)

Taksim Training and Research Hospital

Istanbul, Beyoglu, Turkey (Türkiye)

Taksim Training and Research Hospital

Istanbul, Turkey (Türkiye)

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NCT07717463


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