Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
The Effect of Adjunctive I-PRF on the Outcomes of Minimally-invasive Non-surgical Therapy of Periodontal Intrabony Defects.A Randomized Clinical Trial
Cairo University
48 participants
May 14, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
Eligibility
Inclusion Criteria4
- Patients with periodontitis stage III-IV.
- Presence of at least one intrabony defect with radiographic component ≥ 3mm deep and PPD≥ 6mm (not affecting a tooth with 'hopeless' prognosis).
- Patients willing to sign informed consent and to be in the study until the 6-months follow-up.
- Full-mouth plaque score <30% following step 1 periodontal therapy
Exclusion Criteria2
- Smoker/vaper (currently or in past 5 years).
- Contributory medical history (e.g. cardiovascular disease, diabetes, psychiatric conditions).
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Interventions
I-PRF will be prepared from 10 mL of autologous venous blood and injected into the cleaned defect, followed by placement of a custom-made transparent vacuum-formed stent for 15 minutes to prolong local contact
Participants will receive minimally invasive non-surgical periodontal therapy (MINST) alone using P3 Woodpecker piezoelectric scaler for the selected periodontal intrabony defect
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07722390