RecruitingNCT07726251

Hemodynamic Changes and Trigeminocardiac Reflex During Bimaxillary Orthognathic Surgery

Observational Evaluation of Hemodynamic Parameters Using Routine Intraoperative Monitoring Data in Patients Undergoing Bimaxillary Orthognathic Surgery


Sponsor

Kırıkkale University

Enrollment

18 participants

Start Date

Jun 20, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This observational study aims to evaluate hemodynamic changes occurring during bimaxillary orthognathic surgery using routinely collected intraoperative monitoring data. Heart rate, systolic and diastolic blood pressure, mean arterial pressure, and oxygen saturation will be recorded during different stages of surgery as part of standard clinical care. The study will also evaluate the occurrence of the trigeminocardiac reflex (TCR) and its association with patient characteristics and surgical stages. No additional interventions, laboratory tests, or procedures will be performed beyond routine clinical practice. The findings may contribute to the early recognition and management of intraoperative hemodynamic changes during orthognathic surgery.


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Inclusion Criteria4

  • Adults aged 18-40 years.
  • Patients with an indication for bimaxillary orthognathic surgery.
  • Patients with complete routine intraoperative hemodynamic monitoring data.
  • Patients who provide written informed consent to participate in the study.

Exclusion Criteria7

  • Patients without an indication for bimaxillary orthognathic surgery.
  • Individuals younger than 18 years or older than 40 years.
  • Patients with known cardiovascular disease, including arrhythmia, heart failure, coronary artery disease, or other significant cardiovascular disorders.
  • Patients with systemic diseases, including diabetes mellitus, hypertension, thyroid disorders, or other significant systemic conditions.
  • Patients with diagnosed psychiatric disorders.
  • Patients with incomplete or irregularly recorded intraoperative hemodynamic monitoring data.
  • Individuals who refuse to participate or do not provide written informed consent.

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Locations(1)

Kırıkkale Univesity Faculty of Dentistry

Kirikkale, Kırıkkale, Turkey (Türkiye)

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NCT07726251


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