RecruitingNCT07727512

PCOS and Brain Health

Functional and Structural Impacts of Polycystic Ovary Syndrome (PCOS) on Brain Health


Sponsor

University of Wisconsin, Madison

Enrollment

45 participants

Start Date

Aug 1, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance. 45 reproductive aged (18-45 years) individuals with ovaries, with and without PCOS, will be enrolled to complete brain structure and CBF scans via magnetic resonance imaging (MRI) over 2 testing visits and can expect to be on study for approximately 5 hours over a 1 to 3 month period.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Laboratory Visit and a medical device called MRI Visit for people with pcos. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEMRI Visit

MRI visit will take approximately 1.5 hour (55-60 minutes in MRI) and will involve structural scans of the brain, and scans at rest and while performing cognitive tasks.

OTHERLaboratory Visit

DEXA scan for obtaining body composition, NIH toolbox to assess cognitive test, and optional graded exercise test (GXT).


Locations(1)

University of Wisconsin

Madison, Wisconsin, United States

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NCT07727512


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