RecruitingPhase 2Phase 3NCT07737704

Assessment of a New Enhanced Xenograft in Open Maxillary Sinus Augmentation

Clinical, Radiographic and Histologic Assessment of a New Xenograft Enhanced With Hydrogel in Augmentation of the Maxillary Sinus: A Randomized Controlled Trial


Sponsor

Misr International University

Enrollment

30 participants

Start Date

Aug 10, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Implant supported dental restorations are sometimes challenging with decreased bone height in the posterior maxilla. The goal of this study is to test an augmentation bone substitute in elevating the maxillary sinus floor; in terms of soft tissue reaction, formed bone height as well as structure. Bone substitute will be compared to a graftless method of bone augmentation depending on participants' bodies forming bone in the defective area. Participants will: * Undergo lateral maxillary sinus floor elevation with bone substitute or graftless method. * Record postoperative swelling and pain through the follow up period. * Take radiographs for evaluation of the formed bone before placing dental implants.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Xenograft and maxillary sinus membrane elevation and stabilization. for people with bone augmentation, maxillary sinus elevation, and other related conditions. The study is currently recruiting participants at 3 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALXenograft

hydrogel-enhanced xenograft

OTHERmaxillary sinus membrane elevation and stabilization.

graftless augmentation of the maxillary sinus floor through membrane elevation and stabilization; tenting.


Locations(3)

Suez Canal University

Ismailia, Ismailia Governorate, Egypt

Suez Canal University

Ismailia, Egypt

Suez Canal University

Ismailia, Egypt

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NCT07737704


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