RecruitingNCT07747441

Perfusion Index and Spinal Hypotension in Day-Case Knee Arthroscopy

Predictive Value of Baseline Perfusion Index for Spinal Anesthesia-Induced Hypotension in Healthy Patients Undergoing Knee Arthroscopy: A Prospective Observational Trial


Sponsor

Ankara Etlik City Hospital

Enrollment

150 participants

Start Date

Aug 6, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective observational study aims to investigate the role of the baseline perfusion index (PI) in predicting spinal anesthesia-induced hypotension (SAIH) in ASA I-II patients undergoing day-case knee arthroscopy. Spinal anesthesia is a widely preferred technique for lower extremity surgeries, including knee arthroscopy. However, sympathetic blockade during spinal anesthesia frequently leads to significant hemodynamic instability, particularly hypotension, which can result in adverse perioperative outcomes. While age and baseline blood pressure are traditional risk factors, they often fail to accurately predict the onset of hypotension in healthy populations. The perfusion index (PI), a non-invasive parameter measured via pulse oximetry, reflects peripheral vascular tone and baseline sympathetic activity. An elevated baseline PI indicates baseline vasodilation and a higher susceptibility to sympathectomy, potentially offering an early and non-invasive prediction of SAIH before the hemodynamic collapse occurs. The primary outcome of the study is the incidence of spinal anesthesia-induced hypotension (defined as a mean arterial pressure \< 65 mmHg or a decrease in systolic blood pressure \> 25% from baseline). Secondary outcomes include the onset time of sensory block, and intraoperative ephedrine and fluid requirements.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with anesthesia, spinal, arthroscopy, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Ankara Etlik City Hospital

Ankara, Yenimahalle\Ankara, Turkey (Türkiye)

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NCT07747441


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