RecruitingNot ApplicableNCT07791407

Magnetic Resonance Imaging Based Risk Stratification for Defibrillator Implantation in Heart Failure Patients Requiring Cardiac Resynchronisation Therapy

Magnetic Resonance Imaging Based Risk Stratification for Defibrillator Implantation in Heart Failure Patients Requiring Cardiac Resynchronization Therapy (MADURAI CRT)

Sponsor

Velammal Medical College Hospital and Research Institute

Enrollment

114 participants

Start Date

Aug 1, 2026

Study Type

INTERVENTIONAL

Conditions

Non-ischemic Cardiomyopathy

Summary

This randomized study aimed to compare the efficacy of LBBP without defibrillator vs biventricular pacing with defibrillator (BiV-ICD/CRT-D) in patients with LB-NICM and left ventricular ejection fraction (LVEF) ≤35% risk categorized by CMR imaging.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Biventricular pacing with defibrillator and a medical device called left bundle branch pacing for people with non-ischemic cardiomyopathy. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEleft bundle branch pacing

Capture of left bundle branch fibers by positioning the lead deep inside the proximal inter ventricular septum. Atrial lead will positioned in the right atrium

DEVICEBiventricular pacing with defibrillator

Biventricular pacing with right ventricular ICD lead and coronary sinus lead. Atrial lead will be positioned in the right atrium

Locations(1)

Velammal Medical College Hospital and Research Institute

Madurai, Tamil Nadu, India

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NCT07791407

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