RecruitingNCT07814547

Open vs. Ultrasound-Guided Carpal Tunnel Release

Prospective Multicenter Trial Comparing Open Surgical Decompression Versus Minimally Invasive Ultrasound-Guided Carpal Tunnel Release

Sponsor

AUVA General Trauma Hospital Salzburg

Enrollment

200 participants

Start Date

Jun 1, 2026

Study Type

OBSERVATIONAL

Conditions

Carpal Tunnel Syndrome (CTS)

Summary

Carpal Tunnel Syndrome (CTS) is the most prevalent entrapment neuropathy. Open Surgical Carpal Tunnel Release (OSCTR) remains the gold standard, while minimally invasive Ultrasound-Guided Carpal Tunnel Release (USGCTR) offers potential advantages including reduced postoperative morbidity and faster recovery. This prospective, multicenter observational cohort study compares the clinical outcomes, patient-reported outcomes, and socioeconomic impact of USGCTR versus OSCTR. A total of 200 patients, with 100 patients per cohort, will be included. Patient assignment is based on the participating center's standard of care. Follow-up assessments are performed preoperatively and at 2 weeks, 6 weeks, 3 months, and 12 months after surgery.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Open Surgical Carpal Tunnel Release (OSCTR) and a procedure called Ultrasound-Guided Carpal Tunnel Release (USGCTR) for people with carpal tunnel syndrome (cts). The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREOpen Surgical Carpal Tunnel Release (OSCTR)

Open surgical decompression of the carpal tunnel (OSCTR) is performed at UKH Salzburg as the established standard surgical treatment for carpal tunnel syndrome. The procedure involves open surgical release of the flexor retinaculum. Intraoperative findings and immediate complications are documented.

PROCEDUREUltrasound-Guided Carpal Tunnel Release (USGCTR)

Ultrasound-guided carpal tunnel release (USGCTR) is performed at the University Institute of Radiology of the Paracelsus Medical Private University. The minimally invasive procedure involves release of the flexor retinaculum under continuous sonographic visualization through a minimal incision at the distal forearm or wrist crease. Intraoperative findings and immediate complications are documented.

Locations(2)

AUVA General Trauma Hospital Salzburg

Salzburg, Austria

University Institute of Radiology, Paracelsus Medical Private University Salzburg

Salzburg, Austria

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NCT07814547

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